Electrically Evoked Itch in Human Subjects

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Electrically evoked itch in humans.

We compared itch sensations and axon reflex flare induced by transcutaneous electrical (0.08-8 ms, 2-200 Hz) and chemical (histamine iontophoresis; 100 microC) stimulation. Stimuli were applied to non-lesional volar wrist skin in 20 healthy human subjects and 10 patients with atopic dermatitis. Intensity of evoked itch and pain sensations were rated on a numerical rating scale (NRS) of 0 (no se...

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Recording Electrically-evoked Auditory Brainstem Responses (EABR) in Human Cochlear Implant Subjects

–– Auditory Brainstem Responses (ABR) and Electrically-evoked Auditory Brainstem Responses (EABR) are two closely related exogenous auditory evoked potentials (AEP) elicited from EEG measurements [1]. ABR is used as a hearing screening tool for newborns [2] and general hearing loss [3], while EABR is used in cochlear implant (CI) intraoperative monitoring [4] and speech processor tuning [5]. He...

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Mechanically evoked itch in humans.

When a newly developed experimental method to vibrate vellus hairs on human skin was applied to the face and arm in healthy subjects, intense itch was reproducibly induced on the face, but not on the arm, without any flare reactions. In contrast to histamine-induced itch, mechanically evoked itch was not characterized as burning or stinging by any subjects, and was resistant to histamine H1-rec...

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Electrically evoked myoelectric signals.

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Mouse model of touch-evoked itch (alloknesis)

Lightly touching normal skin near a site of itch can elicit itch sensation, a phenomenon known as alloknesis. To investigate the neural mechanisms of alloknesis, we have developed an animal model. Low-threshold mechanical stimulation of the skin normally does not elicit any response in naive C57/BL6 mice. Following acute intradermal (i.d.) injection of histamine in the rostral back, mechanical ...

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ژورنال

عنوان ژورنال: Frontiers in Medicine

سال: 2021

ISSN: 2296-858X

DOI: 10.3389/fmed.2020.627617